Deguelin‐induced blockade of PI 3K/protein kinase B/ MAP kinase signaling in zebrafish and breast cancer cell lines is mediated by down‐regulation of fibroblast growth factor receptor 4 activity
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چکیده
منابع مشابه
Deguelin‐induced blockade of PI3K/protein kinase B/MAP kinase signaling in zebrafish and breast cancer cell lines is mediated by down‐regulation of fibroblast growth factor receptor 4 activity
Deguelin, a natural component derived from leguminous plants, has been used as pesticide in some regions. Accumulating evidence show that deguelin has promising chemopreventive and therapeutic activities against cancer cells. This study shows that low concentrations of deguelin can lead to significant delay in zebrafish embryonic development through growth inhibition and induction of apoptosis....
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ژورنال
عنوان ژورنال: Pharmacology Research & Perspectives
سال: 2016
ISSN: 2052-1707,2052-1707
DOI: 10.1002/prp2.212